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There are several matches for 'manganese transporter'.
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6809 matches
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organism
protein
1)
Homo sapiens
SLC30A10 - Zinc
transporter
10; Plays a pivotal role in
manganese
transport
.
Manganese
is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. However, elevated levels of
manganese
are cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis. Acts as
manganese
efflux
transporter
and confers protection against
manganese
-induced cell death. Also acts as zinc
transporter
involved in zinc homeostasis. Seems to mediate zinc
transport
into early endosomes and recyc [...]
[a.k.a. R-HSA-425410, NR_046437.1, ENST00000366926]
2)
Homo sapiens
ATP13A1 -
Manganese
-
transporting
ATPase 13A1; Mediates
manganese
transport
into the endoplasmic reticulum. The ATPase activity is required for cellular
manganese
homeostasis. Belongs to the cation
transport
ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
[a.k.a. ENST00000497156, ENST00000357324, ATP13A1-207]
3)
Homo sapiens
SLC39A8 - Zinc
transporter
ZIP8; Acts as a
manganese
and zinc influx
transporter
. Plays a role in
manganese
reabsorption in the proximal tubule of the kidney and in
manganese
uptake into the brain ; Belongs to the ZIP
transporter
(TC 2.A.5) family.
[a.k.a. URS0000D6E6CE, R-HSA-425410, NM_001135146.2]
4)
Homo sapiens
SLC11A2 - Natural resistance-associated macrophage protein 2; Important in metal
transport
, in particular iron. Can also
transport
manganese
, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron
transport
from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria. Belongs to the NRAMP family.
[a.k.a. XP_005268969.1, R-HSA-425410, UPI00001FC234]
5)
Homo sapiens
SLC11A1 - Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and
manganese
)
transporter
involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane
transport
function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...]
[a.k.a. R-HSA-425410, SLC11A1-217, R-HSA-1222556]
6)
Mus musculus
Slc30a10 - Zinc
transporter
10; Plays a pivotal role in
manganese
transport
.
Manganese
is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. However, elevated levels of
manganese
are cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis. Acts as
manganese
efflux
transporter
and confers protection against
manganese
-induced cell death. Also acts as zinc
transporter
involved in zinc homeostasis. Seems to mediate zinc
transport
into early endosomes and recyc [...]
[a.k.a. CCDS15599.1, ZnT-10, 226781]
7)
Mus musculus
Atp13a1 -
Manganese
-
transporting
ATPase 13A1; Mediates
manganese
transport
into the endoplasmic reticulum. The ATPase activity is required for cellular
manganese
homeostasis (By similarity).
[a.k.a. R-MMU-983712, NM_133224, CH466569]
8)
Mus musculus
Slc39a8 - Zinc
transporter
ZIP8; Acts as a
manganese
and zinc influx
transporter
. Plays a role in
manganese
reabsorption in the proximal tubule of the kidney and in
manganese
uptake into the brain.
[a.k.a. NP_001128621.1, NP_080504.3, NM_026228.5]
9)
Mus musculus
Slc11a1 - Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and
manganese
)
transporter
involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane
transport
function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...]
[a.k.a. Slc11a1-201, host resistance locus Bcg/Ity/Lsh, R-MMU-425410]
10)
Drosophila melanogaster
CG42542 - Uncharacterized protein, isoform D; Calcium ion transmembrane
transporter
activity;
manganese
ion transmembrane
transporter
activity; metal ion transmembrane
transporter
activity. It is involved in the biological process described with: calcium ion transmembrane
transport
; Golgi calcium ion
transport
; Golgi calcium ion homeostasis;
manganese
ion transmembrane
transport
.
[a.k.a. FBgn0260659, CG42542-PE, CG42542-PD]
11)
Caenorhabditis elegans
catp-8 - Probable
manganese
-
transporting
ATPase catp-8; Mediates
manganese
transport
into the endoplasmic reticulum. The ATPase activity is required for cellular
manganese
homeostasis.
[a.k.a. C10C6.6, WBGene00007514, C10C6.6.1]
12)
Saccharomyces cerevisiae
PHO84 - High-affinity inorganic phosphate (Pi)
transporter
; also low-affinity
manganese
transporter
; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; cells overexpressing Pho84p accumulate heavy metals but do not develop symptoms of metal toxicity.
[a.k.a. YML123C, 854916, P25297]
13)
Saccharomyces cerevisiae
SMF1 -
Manganese
transporter
SMF1; Divalent metal ion
transporter
; broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal
transport
proteins; Belongs to the NRAMP family.
[a.k.a. YOL122C, D6W1U6, P38925]
14)
Saccharomyces cerevisiae
SPF1 -
Manganese
-
transporting
ATPase 1; P-type ATPase, ion
transporter
of the ER membrane; required to maintain normal lipid composition of intracellular compartments and proper targeting of mitochondrial outer membrane tail-anchored proteins; involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1.
[a.k.a. YEL031W, UPI0000052E71, NM_001178846]
15)
Escherichia coli K12
mntH - Manganese/divalent cation
transporter
; H(+)-stimulated, divalent metal cation uptake system. Involved in
manganese
and iron uptake. Can also
transport
cadmium, cobalt, zinc and to a lesser extent nickel and copper. Involved in response to reactive oxygen.
[a.k.a. b2392, AAC75451.1, manganese/divalent cation transporter]
16)
Saccharomyces cerevisiae
HIP1 - High-affinity histidine permease; also involved in the
transport
of
manganese
ions.
[a.k.a. YGR191W, NP_011707, UPI000012C728]
17)
Saccharomyces cerevisiae
SMF2 - Divalent metal ion
transporter
involved in
manganese
homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal
transport
proteins; Belongs to the NRAMP family.
[a.k.a. YHR050W, UPI0000135AA0, P38778]
18)
Escherichia coli K12
corA - Magnesium/nickel/cobalt
transporter
; Mediates influx of magnesium ions. Can also mediate cobalt and
manganese
uptake. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high (By similarity). Belongs to the CorA metal ion
transporter
(MIT) (TC 1.A.35) family.
[a.k.a. b3816, AAC76819.1, 948351]
19)
Saccharomyces cerevisiae
MNR2 -
Manganese
resistance protein MNR2; Vacuolar membrane protein required for magnesium homeostasis; putative magnesium
transporter
; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs); Belongs to the CorA metal ion
transporter
(MIT) (TC 1.A.35) family.
[a.k.a. YKL064W, P35724, sce:YKL064W]
20)
Saccharomyces cerevisiae
MTM1 - Mitochondrial protein of the mitochondrial carrier family; high affinity pyridoxal 5'-phosphate (PLP)
transporter
, important for delivery of PLP cofactor to mitochondrial enzymes; involved in mitochondrial iron homeostasis and in activating mitochondrial Sod2p by facilitating insertion of an essential
manganese
cofactor.
[a.k.a. YGR257C, 853173, CAA67613.1]
6809 matches
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